Abstract：A quick, easy, cheap, effective, rugged and safe (QuEChER) extraction procedure followed by a liquid chromatography-tandem mass spectrometry (LC-MS/MS) assay was established for the simultaneous determination of amphenicol antibiotics (chloramphenicol, thiabendazole and florfenicol) and the florfenicol metabolite florfenicol amine (FFA) in bullfrog meat. The results showed that there was a good linear relationship between the mass spectrometric response and concentrations of all analytes in the range from 0.1 to 50.0 ng/mL with correlation coefficients all greater than 0.999 1. The limits of detection and quantitation were in the range from 0.007 5 to 0.003 0 μg/kg and from 0.025 to 0.100 μg/kg, respectively. The recoveries from spiked samples were in the range from 94.3% to 97.9%, with relative standard deviation of 0.8% to 3.7%.
黄思聪，龙敏仪. QuEChERS-液相色谱-串联质谱法测定牛蛙肉中酰胺醇类抗生素及其代谢物[J]. 肉类研究, 2019, 33(6): 39-43.
HUANG Sicong, LONG Minyi. Determination of Amphenicol Antibiotics and Metabolite Residues in Bullfrog Meat by QuEChERS-Liquid Chromatography-Tandem Mass Spectrometry. Meat Research, 2019, 33(6): 39-43.
2019, Vol. 33 
