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| Multi-Angle Analysis of the Statement of the World Health Organization Regarding the Carcinogenicity of the Consumption of Red and Processed Meat |
| HU Menghan1, DONG Qingli1,*, LUO Xin2 |
1. School of Medical Instrument and Food Engineering, University of Shanghai for Science and Technology, Shanghai 200093, China;
2. College of Food Science and Engineering, Shandong Agricultural University, Tai’an 271018, China |
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Abstract Based on the existing literature, this mini review conducts a multi-angle analysis of the possible unscientific points in the statement of the International Agency for Research on Cancer (IARC) regarding the carcinogenicity of processed and red meat, and presents our personal opinions and suggestions on this topic. The drawbacks of the epidemiological study are proposed, including the shortcomings of the observational study and statistical analysis. Some state-of-the-art techniques such as organs on chips could be used to establish human dose-response models in the strict sense, thereby addressing the above drawbacks. In addition, it is unscientific that the IARC’s statement just explained the “hazard”, but ignored the “risk”. In this sense, an internationally recognized method called the risk assessment is required to be carried out for assessing the carcinogenicity of processed meat products and red meat, and the resulting report of risk assessment is subsequently applied for decision-making. In terms of meat products processing, the authors point out that it is necessary to progress in technologies and concepts simultaneously, thus accelerating the development of healthy functional meat products such as meat analogues and anti-cancer meat products. Also, emerging fast and non-destructive testing techniques need to be continually developed for the comprehensive control of meat quality and safety. To maintain long-term health, consumers should adopt a scientific diet and living habits, and keep positive moods. The communication among the meat enterprises, scientific research institutions and consumers is also important.
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