Abstract：Taurine is one of the conditionally essential amino acids in the human body and it plays an important role in the
physiological functions of the human body. In this research, our purpose was to evaluate the effect of taurine on immune
functions and antioxidant capacity in animals. A mouse model of immunosuppression was established by intraperitoneal
injection of mice of different ages with cyclophosphamide, and then the immunosuppressed mice were intraperitoneally
injected with various doses of natural taurine physically extracted from bovine liver. After 12 hours, we measured
immunological indicators and antioxidant parameters and correlated immunological indicators with total antioxidant
capacity (T-AOC). The results showed that taurine at both high and low doses had an immunoregulatory effect and improved
antioxidant capacity in immunosuppressed mice of different ages and immune functions and antioxidant capacity in juvenile
and old mice administered with taurine reached or exceeded the normal level. Correlation analysis revealed that there was a
positive correlation between immune functions and antioxidant capacity in mice.
梁肖娜，叶馨阳，孔彦文，张祎炜，杨 梅，曹雪妍，武俊瑞，岳喜庆. 牛肝中牛磺酸对免疫抑制小鼠免疫及抗氧化能力的影响[J]. 肉类研究, 2016, 30(11): 1-5.
LIANG Xiaona, YE Xinyang, KONG Yanwen, ZHANG Yiwei, YANG Mei, CAO Xueyan, WU Junrui, YUE Xiqing. Effect of Taurine from Bovine Liver on Immune Functions and Antioxidant Capacity in Immunosuppressed Mice. Meat Research, 2016, 30(11): 1-5.
