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| Effect and Regulatory Mechanism of Resveratrol on Muscle Fiber Type Conversion: A Review |
| CHEN Qian, ZHANG Jingyue, LIU Yunge, ZUO Huixin, LIANG Rongrong, MAO Yanwei, ZHANG Yimin, YANG Xiaoyin, LUO Xin, ZHU Lixian |
| College of Food Science and Engineering, Shandong Agricultural University, Tai’an 271018, China |
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Abstract As a natural polyphenol compound derived from grapes and other plants, resveratrol has antioxidant, anticancer, antitumor, and cardiovascular protective effects, and has been a research hotspot in many fields. Skeletal muscle is mainly composed of muscle fibers, and the type and composition of muscle fibers are the key factors affecting meat quality. In recent years, more and more studies have begun to focus on the effect of resveratrol on the type transformation of skeletal muscle, and its regulatory mechanism and related signaling pathways have been gradually determined. This paper summarizes recent research on the effects of resveratrol on skeletal muscle fiber type, and reviews the roles of the microRNA, AMPK/SIRT1/PGC-1α, adiponectin and FoxO1 signaling pathways in the regulation of myofiber type conversion. This review is expected to provide theoretical reference for future targeted regulation of muscle fiber type transformation.
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2024, Vol. 38 
