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Computational Investigation on Veterinary Sulfonamide Imprinted Polymers |
CAI Jie,JI Da-sheng,XIONG Han-guo |
College of Food Science and Technology, Huazhong Agricultural University, Wuhan 430070, China |
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Abstract In this study, we computationally investigated preparation of molecularly imprinted polymers (MIPs) that can bind three commonly used veterinary sulfonamides (SFAs) including sulfisoxazole (SIZ), sulfanilamide (SNM) and sulfamethazine (SM2) using methyl methacrylate (MAA) as the functional monomer. The effect of different reaction media on MIPs preparation was analyzed through calculations based on the density functional theory, and the SFAs-MAA binding was explored at the molecular level with the aim of providing theoretical guidance for preparing reasonable molecularly imprinted polymers.
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[1] |
WANG Xiaoyin, SONG Cuiping, SUN Xiaoliang, LI Muzi, CAO Xumin,Q IN Lide, WANG Shuting, SUI Jinyu, WANG Yudong, ZHAO Sijun. Determination of 11 Sulfonamide Residues in Pork by Modified Fluorescamine Precolumn Derivatization-High Performance Liquid Chromatography with Fluorescence Detection[J]. Meat Research, 2022, 36(2): 33-38. |
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